Trade Name: Epsom Salt, Magnesium Sulfate, U.S.P. To initiate therapy, 4 g of Magnesium Sulfate in Water for Injection may be administered intravenously. If this drug is used during pregnancy the woman should be apprised of the potential harm to the fetus. The central and peripheral effects of magnesium poisoning are antagonized to some extent by intravenous administration of calcium. An injectable calcium salt should be immediately available to counteract the potential hazards of magnesium intoxication in eclampsia. Magnesium Sulfate in Water for Injection is intended for intravenous use only. Magnesium Sulfate in Water for Injection should be administered slowly to avoid producing hypermagnesemia. For advice, contact the … Magnesium Sulfate in Water for Injection is supplied as a clear, colorless solution in single-dose flexible plastic container as follows: * Partial fill container 50 mL volume in 100 mL container. Parenteral use in the presence of renal insufficiency may lead to magnesium intoxication. Magnesium Sulfate in Water for Injection is indicated for the prevention and control of seizures in preeclampsia and eclampsia, respectively. A mixture of finely divided magnesium and nitric acid is explosive [Pieters 1957. p 28]. Manufactured for: Contact may cause irritation to eye, skin, and respiratory system. Rockford, IL 61103 U.S.A. Therefore, in the clinical conditions cited below, both forms of therapy are noted, as appropriate. I found this out recently from my son's doctor. Available for Android and iOS devices. Medically reviewed by Drugs.com. Effective anticonvulsant serum levels range from 2.5 to 7.5 mEq/liter. 1946-47]. To report SUSPECTED ADVERSE REACTIONS, contact Mylan at 1-877-446-3679 (1-877-4-INFO-RX) or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. Magnesium Sulfate Safety Data Sheet According to the Hazard Communication Standard (29 CFR 1910.1200) SECTION 1: Product and Company Identification Product identifier Magnesium sulfate Other means of identification None Synonym(s) None Recommended use Agriculture fertilizer Recommended restrictions None known. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. When used judiciously it effectively prevents and controls the convulsions of eclampsia without producing deleterious depression of the central nervous system of the mother or infant. Magnesium Sulfate in Water for Injection is a sterile, nonpyrogenic, clear, colorless solution of Magnesium Sulfate heptahydrate in water for injection. 77, No. The rate of I.V. If you have any questions, ask your doctor or pharmacist.. Exposure to temperatures above 25°C/77°F during transport and storage will lead to minor losses in moisture content. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Virtually every part of our bodies — including our cells, nerves, muscles, bones and hearts — require a steady supply of the nutrient magnesium to maintain normal functioning. Intravenous magnesium should not be given to mothers with toxemia of pregnancy during the two hours preceding delivery. Store at 20° to 25°C (68° to 77°F). At this level respiratory paralysis may occur. Special protective equipment and precautions for firefighters Wear self-contained, approved breathing apparatus and full protective clothing, including eye protection and boots. Magnesium sulfate is one type of magnesium supplement that can help treat symptoms of magnesium deficiency like muscle cramps, fatigue and irritability — plus other common health problems, too, such as constipation. sulfur oxides). Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 3 Dec 2020) and others. Source(s): https://owly.im/a723z. It is a new type non-flammable material made of light weight materials. Been elevating foot when possible. If breathing is difficult, give oxygen. Page: 1 of 3 . infusion. Select one or more newsletters to continue. It has a role as an anticonvulsant, a cardiovascular drug, a calcium channel blocker, an anaesthetic, a tocolytic agent, an anti-arrhythmia drug, an analgesic and a fertilizer. Magnesium prevents or controls convulsions by blocking neuromuscular transmission and decreasing the amount of acetylcholine liberated at the end plate by the motor nerve impulse. If you have rectal bleeding or if you do not have a bowel movement after using magnesium sulfate as a laxative, stop using the medication and call your doctor at once. Thermal decomposition of Magnesium Sulfate Heptahydrate produces irritating vapors and toxic gases (e.g. The pH is 4.5 (3.5 to 6.5). Because magnesium is removed from the body solely by the kidneys, the drug should be used with caution in patients with renal impairment. Belongs to the Following Reactive Group (s) Metals, Elemental and Powder, Active In addition, cases of neonatal fracture have been reported. Flame temperatures of magnesium and magnesium alloys can reach 3,100 °C (5,610 °F), although flame height above the burning metal is usually less than 300 mm (12 in). Follow all directions on the product package. After the initial I.V. For the management of pre-eclampsia or eclampsia, intravenous infusions of dilute solutions of magnesium (1% to 8%) are often given in combination with intramuscular injections of 50% Magnesium Sulfate Injection. Magnesium (Mg++) is an important cofactor for enzymatic reactions and plays an important role in neurochemical transmission and muscular excitability. Heart block also may occur at this or lower serum levels of magnesium. Fiber cement panels are non-combustible building materials and offer amazing performance in fireproof, bending strength and impact resistance. Last updated on Oct 1, 2020. These include flushing, sweating, hypotension, depressed reflexes, flaccid paralysis, hypothermia, circulatory collapse, cardiac and central nervous system depression proceeding to respiratory paralysis. Section I Manufacturer’s name North Country Organics Emergency Telephone Number 802-222-4277 It is unlikely that these minor losses will lead to clinically significant changes within the expiration period. Magnesium Sulfate in Water for Injection is a sterile, nonpyrogenic, clear, colorless solution of Magnesium Sulfate heptahydrate in water for injection. Drink plenty of liquids while you are taking magnesium sulfate. Mylan Institutional LLC Powdered magnesium reacts violently with performic acid [Berichte 48:1139. Magnesium sulfate, MgSO 4, is a colourless crystalline substance formed by the reaction of magnesium hydroxide with sulfur dioxide and air.A hydrate form of magnesium sulfate called kieserite, MgSO 4 ∙H 2 O, occurs as a mineral deposit. 0 0. It is not known whether this drug is excreted in human milk. Continuous administration of Magnesium Sulfate is an unapproved treatment for preterm labor. Relevant identified uses of the substance or mixture and uses advised against Use of the substance/mixture : Laboratory chemicals 1.3. Date Prepared: April 5, 2012. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Cool unopened containers with water. A serum magnesium level of 6 mg/100 mL is considered optimal for control of seizures. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. And if someone is shooting heat-seeking missiles at you, you’d better hope magnesium is flammable: Beyond saving the life of hikers and military pilots, magnesium is also used in signal flares, such as road flares, though other fuels (such as aluminum) are also used. Yahoo is part of Verizon Media. Low magnesium levels don't cause symptoms in the short term. If Magnesium Sulfate is given for treatment of preterm labor, the woman should be informed that the efficacy and safety of such use have not been established and that use of Magnesium Sulfate beyond 5-7 days may cause fetal abnormalities. A mixture of finely divided magnesium and nitric acid is explosive [Pieters 1957. p. 28]. Magnesium Sulfate should be used during pregnancy only if clearly needed. 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